9 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Bloody: Trauma ... tumor • Non-bloody ... parvovirus, HIV, hepatitis ... Joint #Pain #MSK #rheumatology ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... , erythema and WBC ... effusion with few WBCs ... morning • Effusion leukocyte ... B19 • HIV • Hepatitis
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential ... Anemia #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... fraction < 20% Differential ... hepatomegaly, hepatitis ... Disease #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• ↓ WBC • ↓ ... aplastic anemia Treatment ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... pulses, bruis, or blood ... Large Vessel: Blood ... Lab Tests: • CBC ... #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Noninfectious hepatitis ... titers > 1:80 • CBC
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... frequent attacks • Arthritis ... Fluid Testing: • WBCs ... Intracellular (leukocyte ... #treatment #rheumatology