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diagnosis differential hematology treatment infectiousdiseases 1 abscess anesthesia anesthesiology apml bandemia causes cdi cdiff checklist clostridioides clostridium differentiation difficile fungal
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
leukocytes. ... Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... #CBC #hematology
Pathogenesis of meningitis Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
site-specific infections ... changes in the blood ... expression of more leukocyte ... cell (WBC) binding ... #Meningitis #Pathophysiology
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
Intraoperative Sepsis ... ≥ 4mmol.l-1 if infection ... gas, lactate, FBC ... Discuss ongoing management ... Checklist #Diagnosis #Management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
reduced RBC • ... Gamma-irradiated RBC ... Volume Reduced RBC ... • Washed RBC ... Transfusions #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC ... confirm DAH, r/o infection ... reveals increasing blood ... gross hematuria, RBC ... differential #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... Imaging: CXR- pulmonary ... QD until normal WBC ... APML #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Diagnosis and Management ... Diarrhea (>3 BM/d) ± blood ... pain, Fever, ↑WBC ... Perforation) Pathophysiology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... anemia • Sputum/Blood ... Lung #Abscess #pulmonary
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Major blood ... : • Increased leukocyte ... Aspergillosis Pathophysiology ... have positive blood ... Fungal #Diagnosis #Management
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