13 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... APML #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... confirm DAH, r/o infection ... reveals increasing blood ... differential #diagnosis #management ... #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... result from low blood ... hematology #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... response preceding infection ... - NORMAL CSF WBC ... #diagnosis #management ... #treatment #neurology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Diagnosis and Management ... Diarrhea (>3 BM/d) ± blood ... pain, Fever, ↑WBC ... Perforation) Pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... anemia • Sputum/Blood ... Lung #Abscess #pulmonary
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Diagnosis: • Infection ... elevated white blood ... epilepticus Treatment ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... passage • Arterial blood ... gas (ABC) analysis ... ) on room air Treatment ... #treatment #hepatology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... normal CSF white blood ... the underlying pathophysiology ... and cauda equina TREATMENT ... #diagnosis #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... Fluid Testing: • WBCs ... Intracellular (leukocyte ... Diagnose concomitant infection