19 results
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... Agglutinate: Cold ... differential #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... Agglutination - Cold ... membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... practices that could ... or if a primary hematologic ... Diagnosis #Causes #Workup ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Blood smear - RBC ... Monoclonal IgM Includes Disorders ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... majority of the leukocytes ... that involves disorders ... These causes could
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... /µL Workup • Screen ... glucocorticoid treatment ... Differential #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(e.g. primary cold ... lymphoproliferative disorders ... • Intrinsic RBC ... Hemoglobinopathies (e.g. sickle cell ... differential #diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... Red cell distribution ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic