1746 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
Therapeutic Target Levels ... lithium, target levels ... vary depending on treatment ... mortality at a higher level
Vitamin D Deficiency - Classification and Treatment - Insufficiency vs Deficiency
Vitamin D Insufficiency:
 • 25(OH)D Level
Classification and Treatment ... Insufficiency: • 25(OH)D Level ... 50 nmol/L) • Treatment ... Follow-up 25(OH)D levels ... Classification #Treatment
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
with higher CK levels ... , greater level ... after 2 years of treatment
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
Alarm (for CO levels ... measuring COHb levels ... Treatment: 100%
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
- Preventative Treatments ... Cyproheptadine * Level ... #Preventative #Treatment
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Aims to reduce level ... Wilsons #Disease #Treatment
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
• Start pre-treatment ... 48 hours post Treatment ... continued until levels ... rapid lowering of level ... Toxicity #management #treatment
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
boosters used in HIV treatment ... to increase levels ... and increase the levels
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
Disorder Toxicity Levels ... increase lithium levels ... maintenance agent for treatment ... a target serum level ... If levels are high
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... indicate preferred treatment ... the perceived level