15 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Circulation Failure Kidney ... #Chronic #Liver ... #diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Classification ... cardiorenal syndrome) • Liver ... causes: sepsis, meds ... #diagnosis #nephrology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Skin involvement, Kidney ... Alcohol-related liver ... dechallenge • Acute ... #DrugInduced #Liver
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... > 2 • NASH, Chronic ... injury: > 3 • Chronic
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Identification of onset (acute ... vs. chronic) 2) ... history (cardiac, liver ... #EM #IM #Nephro ... #Differential #Algorithm
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... heart failure, liver ... heart failure, liver ... heart failure, liver ... heart failure, liver
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Management Algorithm ... HAV immunity; Liver ... elastographv, liver ... • Liver is the ... #Diagnosis #Management
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... Medications → Stop meds ... #treatment #management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... - Symptoms of chronic ... hepatocellular pattern of liver ... regarding need for treatment
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
adults • Link to chronic ... • Concomitant acute ... deficiency) • Liver ... HAGMA; Paracetamol level ... #management #treatment