44 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... #Chronic #Liver ... Cirrhosis #Hepatology #gastroenterology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... #differential # ... #algorithm #gastroenterology
Perianal Crohn's Disease - IBD Algorithm

 • 5-40% w perianal fistula
 • ↑ risk if colonic
Crohn's Disease - IBD ... Algorithm • ... medical therapy • Chronic ... #Algorithm #gastroenterology ... #management #treatment
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Liver Injury: ... Liver Injury: ... Liver Injury:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... Alcohol-related liver ... dechallenge • Acute ... #DrugInduced #Liver
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Cirrhosis • Chronic ... Hepatopathy • Acute ... (Drug-induced liver ... injury) • Ischemic
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Liver Failure ( ... > 2 • NASH, Chronic ... > 3 • Chronic ... chemistry #diagnosis #differential
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatocellular - Liver ... Artery: Shock Liver ... #Injury #Differential ... #algorithm #hepatology
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Algorithm Upper ... Stabilization Concern for Liver ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential ... #gastroenterology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
unresponsive to treatment ... • Elevated liver ... microscopic colitis Differential ... Inflammatory (IBD ... #gastroenterology