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diagnosis hepatology causes injury saag gradient management obgyn obstetrics transaminitis abnormal aflp chemistry dili drug elevated fatty hepatitis hypertension idiosyncratic
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
albumin gradient ... syndrome, Massive liver ... #albumin #gradient ... #hepatology #differential ... #diagnosis #algorithm
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... tests in pregnancy ... Hepatocellular Pattern #LFTs ... hepatology #diagnosis #differential ... #algorithm
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Serum Ascites Albumin ... - Massive liver ... Veno-occlusive disease - Acute ... fatty liver of ... pregnancy - Myxedema
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Drug #induced #Liver ... #algorithm #gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Hepatocellular Level ... Production: • Albumin ... chemistry #diagnosis #differential ... transaminitis #LFTs
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... fibrosis - Acute ... fatty liver of ... pregnancy 3. ... Causes #diagnosis #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... liver failure rapidly ... develops (DIC, ascites ... Transfer to a liver
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
INR, bilirubin, albumin ... • Cirrhosis/acute ... sarcoidosis) • Liver ... metastasis • Fatty liver ... of pregnancy
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatocellular - Liver ... Artery: Shock Liver ... Toxic: Medication, Pregnancy ... #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Wilson's • Pregnancy ... • Others #LFTs
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