8 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT ... #Algorithm #hematology
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Stabilization Concern for Liver ... GI Bleed: • Peptic ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential ... #gastroenterology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... • Reduced liver ... #hematology #coagulation
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... Idiosyncratic #differential ... #algorithm #gastroenterology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... should be TS and SF level ... hemochromatosis; HIC, hepatic ... #diagnosis #management ... #hepatology #gastroenterology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... causes #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Acquired: • Heparin ... deficiency • Liver ... suggests liver ... these causes are liver ... Acquired: • Liver