19 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
) SAAG ≥ 1.1: ... ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... #gradient #hepatology ... differential #diagnosis #algorithm
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Acute fatty liver ... Mediterranean fever ... #differential #hepatology
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Disease (Cirrhosis ... Complications • Ascites ... Syndrom (HRS) • Liver ... SBP) #ESLD #Liver
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
either made in the liver ... or not by the liver ... the blood The diseased ... liverprof #Diagnosis #Hepatology ... #SAAG #Ascites
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) ... >1.1 g/dl): - Cirrhosis ... - Massive liver ... - Acute fatty liver ... Differential #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... (SAAG>I.I), esophageal ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Diagnosis #causes #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... failure - 3-5% Cirrhosis ... Differential #Diagnosis #hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Differential Diagnosis Algorithm ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... #Hepatology #causes
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... of autoimmune disease ... Liver biopsy findings ... #hepatology
Non-Alcoholic Fatty Liver Disease (NAFLD) Progression / Prognosis Timeline
 • 100 patients → (over 20+ years)
Non-Alcoholic Fatty Liver ... → 95 patients never ... -2 patients LT/Liver-related ... total 98-99 non liver-related ... Prognosis #Timeline #Hepatology