64 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Low serum IgG level ... DDX - Other causes ... : • Nephrotic syndrome ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... #management #treatment
Campylobacter
Clinical 
 • Fever 
 • Abdominal pain 
 • Diarrhea (bloody stools) 
 • Vomiting
Campylobacter Clinical ... • Fever • ... Guillain-Barré syndrome ... • Supportive (infection ... Campylobacter #Diagnosis
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
- Differential Diagnosis ... Leg Pain: • Infection ... entrapment • Infections ... #differential #diagnosis ... extremity #msk #physicalexam
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Knee #Effusions #causes ... #differential #diagnosis ... #msk #physicalexam
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : • Clinical triad ... Labs/Diagnosis: ... C4 complement level
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
Pericarditis on POCUS ... Echocardiogram ... one month ago-pt never ... next day due to infectious ... #clinical #cardiology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... Cardiopulmonary Syndrome ... • Prodrome: fever ... +/- diarrhea Diagnosis ... #management #treatment
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... fungal ringworm infection ... mentagrophytes) Clinical ... #Dermatology #Diagnosis ... #Management #Features
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Causes of spinal ... • Extrinsic Causes ... • Intrinsic Causes ... Infarction - Infection ... #differential #diagnosis