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Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Brucellosis, Q fever ... Mediterranean fever ... , Factitious fever ... DrEricStrong #Fever
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Rickettsial diseases ... • Crohn disease ... Non-Infectious Causes ... #Differential #Diagnosis
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... #differential #diagnosis
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
• Typhoid Fever ... • Drug Fever ... Typhoid Fever (S ... Dengue Fever NOTE ... #Dissociation #diagnosis
Causes of Relative Bradycardia - Note the propensity for intracellular organisms.
Infectious: 
Legionella, Psittacosis, Q fever, Typhoid
Causes of Relative ... , Typhoid fever, ... , Dengue fever, ... #bradycardia #Causes ... #differential #diagnosis
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... of Fever CRITICAL ... - Sickle cell disease ... - Drug fever ... Postmyocardiotomy syndrome #Fever
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Other: • Drug fever ... • Factitious fever ... • Rheumatic fever ... parasites #Fever
Causes of Fever by System #Diagnosis #EM #IM #Fever #Differential #Ddxof
Causes of Fever ... by System #Diagnosis ... #EM #IM #Fever
Differential Diagnosis of Fever and Splenomegaly
 - Typhoid
 - Infective endocarditis
 - Miliary tuberculosis
 - Hodgkin
Differential Diagnosis ... of Fever and Splenomegaly ... Brucellosis #Fever ... #Differential #Diagnosis ... #causes
Systolic Murmurs - Differential Diagnosis Algorithm
Benign / Flow / Hyperdynamic:
 • Pregnancy
 • Fever
 • Anemia
Supravalvular
Pregnancy • Fever ... • Rheumatic Fever ... • Rheumatic Fever ... • Rheumatic Fever ... #Algorithm #causes