22 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
sickle cell hepatic ... Supportive with treatment ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Diagnosis Hepatocellular ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #Differential #Diagnosis ... #algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... Hepatopathy • Acute ... Viral Hepatitis ... ) • Non-hepatic ... #hepatology #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... disease, Hepatic ... dechallenge • Acute ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Alcoholic hepatitis ... fibrosis - Acute ... fatty liver of ... Ascites #Causes #diagnosis ... #differential #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... Alcohol, Viral hepatitis ... table #comparison #diagnosis ... #hematology #deficiency
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... • Cirrhosis/acute ... hepatitis • Infiltrative ... #Differential #Diagnosis ... #causes #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Hepatic ... and hemorrhage Acute ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #differential #diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... Hepatocellular Level ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential #Hepatology