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diagnosis hematology coagulation abnormal hepatology prolonged pt bleeding bruising dic disorders disseminated hemostasis immunecompromised immunocompromised intravascular management nonpalpable palpable petechiae
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Acute fatty liver ... Mediterranean fever ... #differential #
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Differential ... Diagnosis Algorithm ... Hypertension - Hepatic ... disease • Acute liver
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... • Reduced liver ... #hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... (CVID, WAS), (neurologic ... bypass), LFT (liver ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
or venipuncture sites ... DIC • Severe Liver ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... Cholesterol emboli • Septic ... mountain spotted fever ... #nonpalpable #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
• Factor VIII level ... deficiency • Liver ... suggests liver ... are liver function ... Acquired: • Liver
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Diagnosis Algorithm ... Red Flags: • Fever ... #Causes #dermatology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... • Bacteremia/Septic ... Infection #Fever ... #Causes #Hematology
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