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diagnosis hepatology liver injury management druginduced gastroenterology rheumatology table classification compared dermatology drug erythemas function hemochromatosis hepatitis hepatomegaly idiosyncratic liverenzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... (>1000): • DILI ... (Drug-induced liver ... Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... for alternative causes ... #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Diagnosis Algorithm ... effect following treatment ... following EtOH induced ... #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Others #LFTs ... #Causes
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Hepatitis • Drug Induced ... #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... • Iatrogenic: DILI ... #hepatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Discontinuation of causal ... druginduced #lupus #sle #comparison ... #table #rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... diagnosis and treatment ... elevated iron indices ... and hematologic ... hemochromatosis #algorithm
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
• Can be induced ... potential inciting causes ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
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