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Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
• Typhoid Fever ... • Drug Fever ... CLINICAL UTILITY ... Typhoid Fever (S ... Dengue Fever NOTE
Faget Sign - Pulse-Temperature Dissociation Causes of Relative Bradycardia • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... Mountain spotted fever ... , Drug fever
Causes of Relative Bradycardia - Note the propensity for intracellular organisms. Infectious: Legionella, Psittacosis, Q fever, Typhoid
Causes of Relative ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... #bradycardia #Causes
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Brucellosis, Q fever ... Malignancy: - Hematologic ... Mediterranean fever ... , Factitious fever
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
pharyngeal erythema, fever ... pharyngeal erythema, fever ... attack meninges -> Fever ... Sudden onset of fever ... pruritic rash, fever
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Continuous Fever ... (Step ladder: fever ... or no fever • ... Non-Infectious Causes
Spontaneous Bacterial Peritonitis Clinical • Fever • Chills • Abdominal pain Diagnosis
Peritonitis Clinical ... • Fever • ... stain/culture Management ... SBP #Diagnosis #Hepatology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... node biopsy • Clinical ... values supporting hematologic ... udaygulati #FUO #Fever
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
purulent nodules Caused ... mentagrophytes) Clinical ... Hair loss • Fever ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
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