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diagnosis liver causes dehydrogenase dili drug elevated gastroenterology hematology hemolytic hepatitis hepatocellular induced laboratory lactate ldh management neurology seizures testing
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... #Injury #Idiosyncratic ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... #LFTs #hepatitis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... • Hemolytic Anemias ... myocarditis, rheumatic fever ... Sarcoidosis Idiosyncratic ... Dehydrogenase #Elevated #differential
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
of Seizures - Differential ... Diagnosis Algorithm ... Traumatic brain injury ... , Liver failure, ... #Causes #neurology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... bartonella (oroya fever ... #workup #hematology
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