12 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... nervous system (CNS ... Petechial or purpuric rash
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... • Headache • Fever ... Maculopapular rash ... • Common clinical ... meningeal signs (fever
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... • Symptoms: Fever ... • Symptoms: Fever ... opportunistic #InfectiousDiseases
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... proximal joints, Fever ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... #NonHodgkins #comparison ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... arthritis, Skin rash ... fraction < 20% Differential ... management #treatment #rheumatology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
known as rat bite fever ... or Haverhill fever ... infectiosum • Fever ... acute rheumatic fever ... #table #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... weight loss, and fever ... permanent alopecia Differential ... and CNS • Headache ... to: Arthritis, Fever
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... Presentation: Fever ... Manifestations: • Fever ... • Fever and weight ... NTM #Infections #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... and branches • Fever ... Coronary arteries • Fever ... , mucositis • Rash ... chorioretinitis, CNS