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diagnosis hematology management petechiae petechial apml causes differentiation erythematous lesions macrophage mas nikolsky nonpalpable physicalexam purpural purpuric pustular rheumatology skin
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... and a fever may ... localized lesions and fever ... #Diagnosis #Dermatology ... #Algorithm #Differential
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
or absence of fever ... If fever is present ... but without a fever ... #Diagnosis #Dermatology ... #Febrile #Fever
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Petechial or purpuric rash ... kidney failure DDX
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Diagnosis Algorithm ... Red Flags: • Fever ... medication Febrile ... #Causes #dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
petechiae/purpura with fever ... petechiae/purpura with fever ... the patient is afebrile ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... initiation • Differential ... #oncology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Skin Lesions - Differential ... Generalized itchy rash ... Pustules + Fever ... pustulosis • Febrile ... #Diagnosis #Dermatology
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