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diagnosis algorithm hematology causes classification erythematosus pain sle anemia approach arthritis clues comparison hemolytic hodgkins immunecompromised immunocompromised lymphoma management msk
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
acute rheumatic fever ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
, Fever, No muscle ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... the face (many differential ... 9) Unexplained fever ... erythematosus #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... bartonella (oroya fever ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Arthritis: • Joint ... arthropathy • 90% joints ... to: Arthritis, Fever
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Red Flags: • Fever ... Autoimmune Vasculitis (lupus ... deficiency Work ... • Abdominal ultrasound ... Algorithm #Causes #dermatology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Immunocompromised Host - Differential ... Infection • Abscess ... Infection #Fever ... Algorithm #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... Coronary arteries - Fever ... such as systemic lupus ... Vasculitis: • Fevers ... #diagnosis #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology
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