22 results
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Diagnosis and Workup ... Clinical History ... : - Fever, weight ... , Takayasu arteritis ... #Differential #
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... /splenomegaly, liver
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... Summary Clinical ... active ROM +/- fever ... Workup: arthrocentesis ... #Diagnosis #Management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... /arthritis, Skin ... fraction < 20% Differential ... #treatment #rheumatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #AFLP #Fatty #Liver
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver ... ALT ↑ bilirubin level
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... profile, including liver ... ANA and RF (if clinical ... #laboratory #workup ... diagnosis #testing #Rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... Dermatomyositis • Fever ... disease and ILD • Liver ... Liver biopsies show ... • Arthralgia/arthritis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... the spleen or liver ... involvement Differential ... #hematology