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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Microangiopathies #Systemic #Lupus ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Faget Sign - Pulse-Temperature ... , Typhoid fever, ... , Dengue fever, ... 30048576/ #Faget #Sign ... #bradycardia #differential
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Faget's Sign & Liebermeister's ... • Typhoid Fever ... help hone your differential ... #Fagets #Sign #Pulse ... Dissociation #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs ... symptoms #mimickers #differential ... #rheumatology
Differential Diagnosis - Fever of Unknown Origin (FUO)

IMADE mnemonic:
 • Infection
 • Malignancy
 • Autoimmune (Rheumatologic)
Differential Diagnosis ... - Fever of Unknown ... • Autoimmune (Rheumatologic ... udaygulati #FUO #Fever ... UnknownOrigin #Differential
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Fever in Returning ... Regions - Frequent Differential ... without localizing signs ... , Dengue fever, ... Returning #Traveler #differential
Acute Fever in-from the Tropics - Clinical Examination

#Tropics #Traveler #Fever #Differential #Signs #Diagnosis #InfectiousDiseases
Acute Fever in-from ... Tropics #Traveler #Fever ... #Differential # ... Signs #Diagnosis
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Differential Diagnosis ... Continuous Fever ... Brucellosis Faget's Sign ... #Patterns #Differential
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... cholestasis: • Fever ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Diagnosis #Management #Hematology ... #Rheumatology