22 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Berlin Criteria ... without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... #Reactions #hematology
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... of Sickle Cell Crises ... #Hematology #SickleCell ... Manifestations #Workup ... #Algorithm #Ddxof
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Supportive care (transfusions ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... #diagnosis #management ... #hematology #reactions
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... Differential #diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Hematology #Rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Actively maintained fever ... device • Blood transfusion ... hyperthermia crisis (late sign ... Checklist #Diagnosis #Management ... #Workup
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... bartonella (oroya fever ... Differential #Diagnosis #Algorithm ... #workup #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Diuretics, PRBC transfusion ... - 80% have fever ... WBC >100k, + lab signs ... #hematology