44 results
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
criteria: - Fever ... - Typical skin rash ... with concomitant fever ... polyarteritis nodosa #AdultOnset ... #Major #Minor #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... arthritis, Skin rash ... fraction < 20% Differential ... Prunelle Getten #AdultOnset ... #treatment #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Rash • Human ... • Rheumatic fever ... #rashes #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... maculopapular rash ... Systemic AOSD: high fever ... Disease #AOSD #rheumatology ... #diagnosis #management
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
or absence of fever ... If fever is present ... disease, scarlet fever ... but without a fever ... #Febrile #Fever
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous rashes provoke significant angst
in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... and a fever may ... localized lesions and fever ... #Diagnosis #Dermatology ... #Algorithm #Differential
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
30mm length) • Fever ... • Abdominal pain ... Diagnosis #criteria #hematology ... #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Petechial or purpuric rash ... #Hematology #Rheumatology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... instability - New-onset fever ... sulfa-drug - Skin pain ... #Diagnosis #Dermatology ... #Differential #
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... death Neutropenic Fever ... New-onset back pain ... #differential #