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diagnosis hematology treatment syndrome oncology hemophagocytic lymphohistiocytosis causes differential fungal hemeonc infectiousdiseases pulmonary reactions rheumatology abscess acromegaly activation admissions admitting
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... signs and symptoms ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Syndrome #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... Maternal Support - Critical ... #Pregnancy #hepatology ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... Characteristics: Persistent fever ... Persistent high fever ... Pathophysiology ... Fever b.
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... ARDS to explain symptoms ... • Fever and hypotension ... pulmonary edema) • Fever
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Summary Epidemiology ... renal failure Clinical ... General: fever, ... syndrome: ACUTE, fever ... presentation with fever
Myocarditis 5 Principles of Myocarditis: 1. Build clinical suspicion 2. Decide on EMBx 3. Manage acute cardiac injury 4. Manage chronic
Build clinical suspicion ... myocarditis Clinical ... Presentation: - Fever ... Myocarditis #diagnosis #management ... #cardiology #summary
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Signs/Symptoms: ... cystitis, may have fever ... infection, such as fever ... Pathophysiology:
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