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diagnosis management dermatology reactions rheumatology blood hemophagocytic hodgkins lymphohistiocytosis lymphoma photo product syndrome transfusion activation anemia antimda5 antimda5dm aplastic cellulitis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver ... ALT ↑ bilirubin level
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... Treatment: •
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
rapidly evolving rash ... Rapid onset of fever ... sepsis: chronic liver ... #cellulitis #dermatology ... #legs #clinical
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... the spleen or liver ... #oncology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... #oncology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... auricular papules Clinical ... Dermatomyositis • Fever ... disease and ILD • Liver ... Liver biopsies show
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
, but without treatment ... ) ▪ Malaise, fever ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Case of Fitz-Hugh-Curtis (FHC) on CT 28F +4d RUQ pain worse w/ inspiration, 102F fever, no vaginal
inspiration, 102F fever ... vaginal discharge, rash ... enhancement of liver ... FitzHughCurtis #FHC #CT #Clinical ... #Radiology #Perihepatitis
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