21 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... accumulation of clinical ... : fever +++, hepatosplenomegaly ... , ↓ Fibrinogen level ... Treatment: •
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Petechial or purpuric rash ... thrombocytopenia • Liver
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... Rapid onset of fever ... sepsis: chronic liver ... #cellulitis #dermatology ... #legs #clinical
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... PBC, PSC, IgG4, HLH ... disease: > 2 • NASH ... intestines, white blood ... diagnosis #algorithm #hepatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... #diagnosis #comparison
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... #oncology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... Dermatomyositis • Fever ... onset [33-74%] • Blood ... disease and ILD • Liver ... Liver biopsies show
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... the spleen or liver ... #oncology #diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
, but without treatment ... ) ▪ Malaise, fever ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology