145 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Associated - SLE ... mountain spotted fever ... #hematology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... #Management #Hematology ... #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... • Rheumatic fever ... IBD • RA • SLE ... #differential #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... , Rheumatic fever ... • New murmur, fever ... #rheumatology
Temporal (Giant cell) Arteritis 
Risk Factors:
 • Age (almost never occurs before age 50) 
Clinical:
 •
• Age (almost never ... before age 50) Clinical ... GiantCell #Arteritis #Diagnosis ... #Rheumatology #
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... mentagrophytes) Clinical ... Hair loss • Fever ... Lymphadenopathy Treatment ... #Diagnosis #Management
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Causes of Pericardial ... Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... Mediterranean Fever ... #Causes #cardiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: fever +++, hepatosplenomegaly ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... test, ANA (e.g., SLE ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Presentation: • Fever ... , Cough • +/-Nausea ... Criteria - Fever ... KD #vasculitis #rheumatology ... #management #treatment