30 results
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... criteria: - Fever ... with concomitant fever ... Abnormalities in liver ... #Major #Minor #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... - Nonremitting fever ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology ... #Rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... should be TS and SF level ... A liver biopsy can ... of liver disease ... #gastroenterology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiency • Liver ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology #
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Daily high spiking fever ... - Fever spikes ... Fever of at least ... /splenomegaly, liver ... AOSD #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... Systemic AOSD: high fever ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
rarely occurs in adults ... Presentation: • Fever ... Diagnostic Criteria - Fever ... KD #vasculitis #rheumatology ... diagnossi #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... diagnosis #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
also observed in adults ... following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... diseases: SLE+++, Adult-onset ... Treatment: • ... #summary #rheumatology