12 results
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... fever without source ... #Diagnosis #Management ... #Pediatrics #Peds ... Stratification #Fever
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
to identify low-risk ... empiric antibiotic treatment ... Diagnosis #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Attempt if high risk ... Subacute-Acute: • Common: fever ... APML #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
pneumonia • DM risk ... : • 80% have fever ... Blood cultures • CXR ... early disease) • CXR ... westermani • Other: TB
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... : • Fever • Weight ... and Culture • CXR ... Inhibitor: • Risk ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... frequently affects infants ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... : • Fever • Weight ... and Culture • CXR ... Inhibitor: • Risk ... #Diagnosis #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... devices, especially infants ... amphetamines) Toxic: • Radiologic ... Checklist #Diagnosis #Management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... inflammatory response Risk ... sex • Metabolic syndrome ... 12-24 Hours • Fever ... #treatment #rheumatology