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diagnosis management hematology cardiology erythematosus infectiousdiseases sle syndrome systemic activation apml clinical differential differentiation echocardiogram fungal hodgkins infections lymphoma macrophage
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... effusion, Restrictive lung ... Pericarditis, Endocarditis ... symptoms #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Skin Disease Classification ... Non-autoimmune rheumatologic ... • Libman-Sacks endocarditis ... to: Arthritis, Fever
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... rash) • Heart, lung ... Treatment: • Corticosteroids
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Renal Failure Treatment ... #oncology
Tricuspid Valve Endocarditis on POCUS Echocardiogram Patient with active IVDU presents with fever, sepsis. More likely
Tricuspid Valve Endocarditis ... presents with fever ... frequently have lung ... emboli (see CT cor ... Echocardiogram #clinical #cardiology
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 Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... -95% of cases) Classification ... Hodgkin Lymphoma Treatment ... lymphoma #diagnosis #classification ... #hematology #oncology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... night sweats, fever ... hematuria, + RF Treatment ... Persistent bacteremia/fevers ... Differential #Diagnosis #cardiology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... pulmonary symptoms • Rheumatologic ... infection • Cough, fever ... • Isolated fever ... arthritis, and endocarditis
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