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diagnosis hematology management anemia apml chronic classification cll differentiation hodgkins lymphocytic lymphoma syndrome workup
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... megaloblastic anemia Treatment ... if neutropenic fever ... to MDS or acute leukemia ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... virus (EBV) • Leukemia ... index < 2 • EPO Level ... anemia Treatment ... #Anemia #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Headaches, bone pain, fever ... manifestations, hypoxia, CXR ... Lymphadenopathy • HSM • Fevers ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Pure red cell aplasia ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Renal Failure Treatment ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... cycles without XR ... classification #hematology ... #oncology #management
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