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diagnosis management differential hepatology syndrome oncology algorithm dermatology disease hemophagocytic lymphohistiocytosis reactions vasculitis blood classification comparison gastroenterology hemeonc hepatopulmonary infections
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
diagnosis and treatment ... symptoms, elevated liver ... A liver biopsy can ... of liver disease ... and hematologic
Liver Abscess • Pyogenic abscess, accounts for 80% of abscess. • Amebic abscess due to Entamoeba histolytica, accounts for 10%. • Fungal
Liver Abscess • ... 50% of solitary liver ... occur in the right Liver ... • Fever in 90% ... cm Continuous fever
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiency • Liver ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... , vomiting, abdominal ... malaise) → Acute liver ... Transfer to a liver
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... PBC, PSC, IgG4, HLH ... CA, small cell lung ... diagnosis #algorithm #hepatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... effusion, Restrictive lung ... valve lesions Abdominal ... symptoms #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Characteristics: Persistent fever ... Persistent high fever ... - Elevated liver ... Fever b. ... Diagnosis #Management #Hematology
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