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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Differential Diagnosis - Fever of Unknown Origin (FUO)

IMADE mnemonic:
 • Infection
 • Malignancy
 • Autoimmune (Rheumatologic)
Differential Diagnosis ... - Fever of Unknown ... • Autoimmune (Rheumatologic ... udaygulati #FUO #Fever ... #diagnosis #IMADE
Temporal (Giant cell) Arteritis 
Risk Factors:
 • Age (almost never occurs before age 50) 
Clinical:
 •
• Age (almost never ... GiantCell #Arteritis #Diagnosis ... #Rheumatology #
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Differential Diagnosis ... Continuous Fever ... (Step ladder: fever ... #Differential #Diagnosis
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... #differential #diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Fever in Returning ... Frequent Differential Diagnoses ... Symptoms: • Fever ... , Dengue fever, ... #differential #diagnosis
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... cholestasis: • Fever ... Liver transplant ... Hepatobiliary #hepatology ... #differential #diagnosis
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... values supporting hematologic ... udaygulati #FUO #Fever ... UnknownOrigin #workup #diagnosis
Causes of Relative Bradycardia - Note the propensity for intracellular organisms.
Infectious: 
Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... #differential #diagnosis
Ever had a #traveler come in to your clinic with #fever and you were not sure
Ever had a #traveler ... your clinic with #fever ... differentials #diagnosis ... infectiousdisease #fever