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diagnosis differential injury lfts causes nonalcoholic transaminitis fatty gastroenterology treatment acute alcoholic chronic nash abnormal aclf aflp aih alcohol arld
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... 100-500): • NAFLD ... (>1000): • DILI ... (Drug-induced liver ... LouLectures #Liver
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Alcohol-related liver ... disease, Hepatic ... #Liver #Injury ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... or symptoms of liver ... disease 6-9 mo ... Drug #induced #Liver ... gastroenterology #algorithm
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... disease, liver ... support, or liver ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... Antitrypsin • Other: NAFLD ... Artery: Shock Liver ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... antitrypsin • Other: NAFLD ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
disease algorithm ... or liver disease ... disease; NFS, NAFLD ... #NAFLD #algorithm ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... #injury #hepatitis ... differential #diagnosis #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... ALT < 5x ULN • NAFLD ... • Cholestatic disease ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... Metabolic: Wilson Disease ... • Autoimmune hepatitis ... • Iatrogenic: DILI ... Diagnosis #causes #hepatology
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