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Focused evaluation algorithm for acute liver injury

#Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
for acute liver ... injury #Liver ... #Injury #Acute ... #Evaluation #Algorithm ... #Diagnosis #Hepatology
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes of Acute ... Liver Injury #Diagnosis ... #Hepatology #Acute ... #Liver #Injury ... Incidence #Table #Failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... Injury (DILI) ... EmoryGastroHep #ACLF #Acute ... #Hepatology #gastroenterology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe Acute ... Liver Injury ... - Drug-Induced liver ... injury - Viral ... #Differential #Hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... cholestasis: • Fever ... liver failure ... Liver transplant ... Hepatobiliary #hepatology
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
manifestations of acute ... liver failure ... Subclinical myocardial injury ... lung injury, ... #liver #failure
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Autoimmune hepatitis, Acute ... #Injury #Differential ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injuryliver ... failure 1) Hepatocellular ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Liver Injury: ... differential #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... Liver Failure ( ... injury < 26 weeks ... Hepatocellular Level ... #differential #Hepatology