Lever hepatology diagnosis classification management algorithm syndrome hepatitis acute injury

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Causes of Severe Acute Liver Injury
- Ichemic hepatitis
- Acute biliary obstruction
- Drug-Induced liver

Liver Injury ... - Drug-Induced liver ... injury - Viral ... #Differential #Hepatology ... #Diagnosis

for acute liver ... injury #Liver ... #Injury #Acute ... #Evaluation #Algorithm ... #Diagnosis #Hepatology

Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
• Infectious: Hepatitis C, A,

Liver Injury - Differential ... Diagnosis Hepatocellular ... obstruction, HELLP Syndrome ... #Acute #algorithm ... #hepatology

Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)

Acute-on-Chronic ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... #diagnosis

Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury:
• Hepatic vein:

Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... #injury #hepatitis ... #algorithm #hepatology

Patterns of Liver Injury
Transaminase Levels:
> 50x normal - Ischemic Hepatitis
> 20x normal

Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... #Injury #hepatology ... #differential #diagnosis

Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500):
• NAFLD
• Cirrhosis
•

- Differential Diagnosis ... Hepatopathy • Acute ... Viral Hepatitis ... injury) • Ischemic ... #hepatology #transaminitis

Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,

Stepwise Diagnosis ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology

Hepatomegaly - Differential Diagnosis Algorithm
Malignant
• Primary Carcinoma
• Metastases
• Lymphoma
• Leukemia
• Polycythemia

- Differential Diagnosis ... Algorithm Malignant ... Non-Malignant • Fatty Liver ... • Budd-Chiari Syndrome ... #Hepatology

Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver

: Liver Injury ... Infections: Hepatitis ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis

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