13 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... differential #Diagnosis #Management ... #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Injury (DILI) ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... • Iatrogenic: DILI ... week • Direct bilirubin ... Elevation: • Bilirubin ... diagnosis #algorithm #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... 10x ULN), ↑Tbili/Dbili ... #Pregnancy #hepatology ... #pathophysiology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
UGT1A1 activity level ... of hemolysis or liver ... and stress may cause ... #hepatology #diagnosis ... #gastroenterology
Fontan-Associated Liver Disease

By Dr. Andrew Yu @michaelandrewyu via @EmoryGastroHep

#FALD #Fontan #Associated #Liver #Disease #gastroenterology #hepatology #pathophysiology
Fontan-Associated Liver ... Fontan #Associated #Liver ... #Disease #gastroenterology ... #hepatology #pathophysiology ... #diagnosis #management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
out additional causes ... evaluation for other causes ... If other causes ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... slightly elevated • Bilirubin ... or higher • Liver ... diagnosis #workup #hepatology