21 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
syndromes Clinical ... is the main clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... index < 2 • EPO Level ... result from low blood ... #hematology #diagnosis ... #management
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
blood tests. ... blood tests, synthetic ... /or suspicious clinical ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology
Hepatopulmonary Syndrome - Echocardiogram (A4c) with bubble study showing delayed right-to-left shunt consistent with intrapulmonary shunt
68M
Hepatopulmonary Syndrome ... Echocardiogram (A4c ... intrapulmonary #cardiology #clinical ... #pocus #hepatology ... #a4c
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... passage • Arterial blood ... gas (ABC) analysis ... #treatment #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
UGT1A1 activity level ... of hemolysis or liver ... as jaundice on clinical ... bilirubin in the blood ... Congenital #bilirubin #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Highly variable clinical ... Anti-LKM & Anti-ALC ... Hepatitis (eg Viral) Management ... AIH #Diagnosis #Management ... #Hepatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... eosinophil count (AEC ... than 1500 and clinical ... eosinophilia with blood ... eosinophilia #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology