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diagnosis hematology blood neutropenic reactions activation anemia aplastic apml classification criteria differentiation hepatopulmonary hodgkins lymphoma macrophage mas nec rheumatology transfusion
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
for Neutropenic Enterocolitis ... • Neutropenia (ANC ... 30mm length) • Fever ... Diagnosis #criteria #hematology ... #oncology
Typhlitis - Neutropenic Enterocolitis Pathophysiology: • Chemo → friable intestinal mucosa → bacterial translocation +/- perforation Presentation: •
- Neutropenic Enterocolitis ... not abate until ANC ... #Neutropenic #Enterocolitis ... #diagnosis #management ... #oncology #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... ALT ↑ bilirubin level ... Fibrin degradation products ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... RBCs (stored at 4C ... Transfusions #diagnosis #management ... #hematology #reactions
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Diagnosis and Management ... Arterial blood gas (ABC ... hepatopulmonary #syndrome ... #treatment #hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood products contain ... of transfused products ... RBCs (stored at 4C ... Transfusion #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... genes and gene products ... classification #hematology ... #oncology #management
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