13 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Pre-eclampsia 2) ... AIHA, Transfusion reactions ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Differential #Diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Fever >38.5 2. ... Exanthematous Pustulosis Management ... SinaiBmoreIMRes #DRESS #Syndrome ... dermatology #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
: 1) Childhood 2) ... Reticulocyte index < 2 ... • EPO Level ↑ • ... Aplastic #Anemia #oncology ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... Increased soluble IL-2 ... #Diagnosis #Management ... #Hematology #Rheumatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... Sx include: fever ... RBCs (stored at 4C ... Transfusion #diagnosis #management ... #hematology #reactions
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... common in APL (2- ... Moderate > 2/3 and ... APML #diagnosis #management ... #hematology #oncology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... Sx include: fever ... RBCs (stored at 4C ... Transfusions #diagnosis #management ... #hematology #reactions
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... anatomic shunt (Type 2) ... Arterial blood gas (ABC ... hepatopulmonary #syndrome ... #treatment #hepatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... Hyperuricemia 2. ... A reaction to phagocytosed ... sex • Metabolic syndrome ... Indications • ≥2
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... the first 1 to 2 ... decrease in HIV-1 RNA level ... starting ART < 2 ... Differential #Diagnosis #Management