8 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Syndrome #Diagnosis #Management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
sequestration and activation ... ARDS to explain symptoms ... • Fever and hypotension ... pulmonary edema) • Fever ... diagnosis #comparison #table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Non-autoimmune rheumatologic ... : • Symptoms limited ... to: Arthritis, Fever ... Chronic B-cell activation
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... HLH signs and symptoms ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... General: fever, ... skin (16-32%): lupus ... syndrome: ACUTE, fever ... presentation with fever
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Fever, cough ... • Rheumatologic ... infection • Cough, fever ... • Isolated fever ... Fungal #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Characteristics: Persistent fever ... Common Signs and Symptoms ... Persistent high fever ... Fever b. ... #Hematology #HemeOnc
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
- Anasarca - Fever ... including systemic lupus ... disease, severe fever ... and the systemic symptoms ... #rheumatology #