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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... Idiosyncratic #differential ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... disease, liver ... support, or liver ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... Transaminitis #diagnosis #differential ... #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... disease work up - Liver ... Calling #Referral #Hepatology ... #Gastroenterology
Miliary Tuberculosis 
Hematogenous dissemination of Mycobacterium tuberculosis 
Clinical: 
 • Failure to thrive 
 • Fever
to thrive • Fever ... and joints • Liver ... Tuberculosis #TB #Pulmonary ... #InfectiousDiseases
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Causes of Acute Liver ... Injury #Diagnosis #Hepatology ... #Acute #Liver # ... Injury #Causes #Differential
Liver Mass Differential Diagnosis
Solid:
 • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 •
Liver Mass Differential ... Cystadenoma, Polycystic liver ... Echinococcus #Liver ... #Mass #Differential ... #Diagnosis #hepatology
Causes of Granulomatous Liver Diseases - Differential Diagnosis
Infections (Bacterial, Viral, Fungal, Parasitic)
Malignancy
Autoimmune
Drugs/Toxins
Others

#Granulomatous #Liver #hepatic #granulomas #Differential
Granulomatous Liver ... Diseases - Differential ... Granulomatous #Liver ... hepatic #granulomas #Differential ... #Diagnosis #hepatology
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Syndrom (HRS) • Liver ... SBP) #ESLD #Liver ... Complications #diagnosis #management ... #summary #hepatology
Liver Mass - Differential Diagnosis Algorithm
Benign Cystic 
 • Cyst
 • Polycystic Liver Disease
 • Caroli's
Liver Mass - Differential ... • Polycystic Liver ... Colon, Breast) #Liver ... #Mass #Hepatology ... #Differential #