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diagnosis management druglevels ranges table therapeutic adjuvant amiodarone antidote clozapine colchicine corticosteroids digitalis digoxin hantavirus indications induced infections leucovorin lung
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. For lithium, target
vary depending on treatment ... mortality at a higher level ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table #Monitoring
Therapeutic Drug Level Monitoring Carbamazepine - Sample immediately before next dose (trough) Clozapine - Sample immediately
Therapeutic Drug Level ... Monitoring Carbamazepine ... at anytime if toxicity ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Prodrome: fever ... • Autopsy PCR Treatment ... Supportive: ICU monitoring ... #microbiology #infectiousdiseases
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Digoxin Pharmacology and Monitoring • Digoxin’s half-life is 30-45 hours in healthy adults • When monitoring
Digoxin Pharmacology ... and Monitoring ... Kat_Watson #Digoxin #Pharmacology ... #Monitoring #toxicology ... #management #toxicity
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... #Toxicity #Diagnosis ... #Pharmacology
Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... edema, myopathy Hematologic ... Renal failure, Liver ... #Toxicology #Phases ... #Pharmacology #
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... Fever 4. ... macrophages Treatment ... diagnosis #management #Toxicology
Methotrexate Toxicology Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... evidence of marrow toxicity ... #Toxicity #Management ... #Pharmacology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
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