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diagnosis management monitoring druglevels rheumatology table therapeutic adjuvant amiodarone antidote clozapine colchicine corticosteroids dermatology digitalis digoxin dress emergencies encephalopathy hemeonc
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. For lithium, target
vary depending on treatment ... Therapeutic range ... mortality at a higher level ... #Therapeutic #Ranges ... #Toxicology #Pharmacology
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Therapeutic Drug Level Monitoring Carbamazepine - Sample immediately before next dose (trough) Clozapine - Sample immediately
Therapeutic Drug Level ... at anytime if toxicity ... Sample trough level ... #Therapeutic #Ranges ... #Toxicology #Pharmacology
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... #Toxicity #Diagnosis ... #Pharmacology
Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... edema, myopathy Hematologic ... Renal failure, Liver ... #Toxicology #Phases ... #Pharmacology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... - 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Medication/Drug toxicity ... elevated protein level ... persistent altered level ... epilepticus Treatment ... underlying cause • Treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
phase typically ranges ... Fever >38.5 2. ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... → no immediate treatment ... ICANS: altered level ... after CRS) - Treatment ... pleural effusions - Treatment
Digoxin Pharmacology and Monitoring • Digoxin’s half-life is 30-45 hours in healthy adults • When monitoring
Digoxin Pharmacology ... despite reference ranges ... Kat_Watson #Digoxin #Pharmacology ... #Monitoring #toxicology ... #management #toxicity
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