10 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs #Antivirals #table ... #treatment #hcv ... #medications #infectiousdisease ... #hepatology #HepC ... HepatitisC #Management #Pharmacology
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug Level ... at anytime if toxicity ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... metabolized in the liver ... #Toxicity #Diagnosis ... #Pharmacology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... edema, myopathy Hematologic ... Renal failure, Liver ... #Toxicology #Phases ... #Pharmacology #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... respiratory distress syndrome ... Fever 4. ... macrophages Treatment ... diagnosis #management #Toxicology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... evidence of marrow toxicity ... #Toxicity #Management ... #Pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic