41 results
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... of acute liver ... abnormalities Liver ... #liver #failure ... #Signs #Symptoms
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... - Liver Parenchyma ... Artery: Shock Liver ... Sophia_Hayes_MD #Liver ... #Acute #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... • Hepatic vein: ... Liver Injury: ... Liver Injury:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Alcohol-related liver ... disease, Hepatic ... dechallenge • Acute ... #Injury #Diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... • Cirrhosis/acute ... sarcoidosis) • Liver ... metastasis • Fatty liver
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... of cholestatic disease ... replaced by non-hepatic ... disease: > 2 ... #chemistry #diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... disturbance (obstructed liver ... Highest • Bone • Liver ... elevation DDX of Hepatic
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Clinical Examination ... for Liver and Biliary ... physicalexam #cirrhosis #liver ... #disease #signs ... #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Pathogenesis and clinical ... #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... ongoing ↑ LFTs or symptoms ... of liver disease ... Drug #induced #Liver ... gastroenterology #algorithm