11 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... Phagocytosis of blood ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... following: • Fever ... lymph node, or liver ... #management #treatment ... #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Summary Lung ... Pathophysiology ... anemia • Sputum/Blood ... decubitus - air fluid level
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Summary A defect ... the setting of liver ... passage • Arterial blood ... • Underlying liver ... hypertension • Liver
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Summary - GrepMed ... malignancy Pathophysiology ... GH stimulates liver ... • Serum IGF-1 level ... adenoma, ↓(TFT, LH
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Summary Epidemiology ... survival is 93-95% Pathophysiology ... anterior/posterior MSK ... heart (2-5%), liver ... #Management #Signs
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
One Pager Summary ... donors (due to anti-HLA ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... donors (due to anti-HLA ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... DIC • Severe Liver ... #Coagulation #diagnosis ... causes #treatment #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... Summary 3 Conditions ... double contour sign ... +Radiographic signs ... #rheumatology