9 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : • Common: fever ... Imaging: CXR- pulmonary ... APML #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... - ACS, AKI, acute ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... cirrhosis • Intra-pulmonary ... ) on room air Treatment ... hepatopulmonary #syndrome ... #treatment #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Torsemide) • Acute ... pulmonary edema ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
before beginning treatment ... cardiac output - Acute ... pulmonary edema ... - Compartment syndrome ... peritonitis - Acute
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
pleural effusions • Acute ... toxicity (e.g., acute ... respiratory distress syndrome ... Fever 4. ... #diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... Culture Positive: • Acute ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome ... hematuria, + RF Treatment