19 results
Flutycosine - Antibiotics Class Overview
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Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Antibiotics Class Overview ... B for initial management ... - Virtually never ... - Drug levels ... #Pharmacology #Antibiotics
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the ... Treatment of COVID-19 Infection ... highlighted circle= clinical ... Treatment #COVID19 #Pharmacology ... #Table #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , ↓ Fibrinogen level ... immune deficiency, Drugs ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antibiotics Class Overview ... vs Candida -> Drug ... usually works clinically ... salvage therapy, never ... Anidulafungin #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia - Overview ... Aplastic Anemia Clinical ... - Cytotoxic drugs ... index < 2 • EPO Level ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
is the main clinical ... SLE], AOSD) • Infection ... ) • Sepsis • Drug-induced ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... Infections 2. ... Drugs 5. ... Urticaria #diagnosis #rheumatology ... #comparison #table
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... characteristic features Clinical ... Active TB: • Fever ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... characteristic features Clinical ... Active TB: • Fever ... TB #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Syndrome (PRES) Overview ... Diagnosis: • Infection ... abnormality, Medication/Drug ... elevated protein level ... Syndrome #diagnosis #management